Hippocampal Subfield Volumes in First Episode and Chronic Schizophrenia
نویسندگان
چکیده
منابع مشابه
Hippocampal Subfield Volumes in First Episode and Chronic Schizophrenia
BACKGROUND Reduced hippocampal volume in schizophrenia is a well-replicated finding. New imaging techniques allow delineation of hippocampal subfield volumes. Studies including predominantly chronic patients demonstrate differences between subfields in sensitivity to illness, and in associations with clinical features. We carried out a cross-sectional and longitudinal study of first episode, su...
متن کاملNeuropsychological correlates of hippocampal volumes in first episode psychosis.
1 Research Unit, Institute of Mental Health/Woodbridge Hospital, Singapore 2 Early Psychosis Intervention Programme, Institute of Mental Health/Woodbridge Hospital, Singapore 3 Department of Neuroradiology, National Neuroscience Institute, Singapore 4 National Neuroscience Institute, Singapore 5 Biostatistics Unit, Faculty of Medicine, National University of Singapore Address of Correspondence:...
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BACKGROUND Mismatch negativity (MMN) is an event-related brain potential that is sensitive to stimulus deviation from a repetitive pattern. The MMN is thought primarily to reflect the activity of sensory memory, with, at most, moderate influences of higher-level cognitive processes, such as attention. The MMN is reported to be reduced in patients with chronic schizophrenia. However, it is unkno...
متن کاملHippocampal and superior temporal gyrus volume in first-episode schizophrenia.
T he article by Velakoulis et al 1 reported the important finding of hippocampal volume reduction in first-episode schizophrenia and interpreted it as evidence in support of a neurodevelopmental model of this disorder. The authors stated that " no [pre-vious] studies have examined the specificity of this finding to first-episode schizophrenia, compared with first-episode affective psychosis. " ...
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BACKGROUND It has been proposed that the hippocampus is a potential site for a neurodevelopmental lesion in schizophrenia. While smaller hippocampal volumes have been described in chronic schizophrenia, there have been few magnetic resonance imaging studies in first-episode psychosis. Furthermore, no studies have examined the specificity of this finding to first-episode schizophrenia, compared ...
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ژورنال
عنوان ژورنال: PLOS ONE
سال: 2015
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0117785